Journal: PLoS ONE

Article Title: Cathepsin K Is Present in Invasive Oral Tongue Squamous Cell Carcinoma In Vivo and In Vitro

doi: 10.1371/journal.pone.0070925

Figure Lengend Snippet: The knockdown of cathepsin K mRNA has significantly decreased the invasion of HSC-3 shRNA CTSK cells in the myoma organotypic model when compared with HSC-3 shRNA control cells (A–B). HSC-3 shRNA CTSK cells showed a reduction in cathepsin K mRNA levels when compared with wild type cells and HSC-3 cells transfected with a control shRNA (scramble) *p<0.0001 (C). The invasion depth, invasion area, and invasion index were all significantly reduced for HSC-3-shRNA CTSK cells (*p = 0.0006, **p<0.0001, and ***p = 0.0008, respectively) (D–F). Scale bars 200 µm.

Article Snippet: CTSK shRNA and control shRNA lentiviral particles (reference numbers sc-29936-V and sc-108080) were purchased from Santa Cruz Biotechnology (USA).

Techniques: Knockdown, shRNA, Control, Transfection

Journal:

Article Title: Structural basis of the inhibition of class A β-lactamases and penicillin-binding proteins by 6-β-iodopenicillanate

doi: 10.1021/ja9051526

Figure Lengend Snippet: BIP minimum inhibitory concentration tests on bacterial strains

Article Snippet: Table 2 Bacterial Strain MIC (μg/ml) BIP Ampicillin Proteus mirabilis ATCC 29936 64 32 Escherichia coli ATCC 8739 256 <2 Citrobacter freundii ATCC 8090 64 32 Pseudomonas aeruginosa ATCC 27853 >512 >512 Klebsiella pneumoniae ATCC 13883 256 64 Enterococcus faecalis ATCC 7937 256 4 Enterococcus faecalis ATCC 29212 16 <2 Enterococcus faecium ATCC 19434 128 32 Enterococcus hirae ATCC 8790 128 32 Micrococcus luteus ATCC 9341 <2 <2 Listeria monocytogenes ATCC 14780 64 <2 Listeria innocua ATCC 33090 128 <2 Staphylococcus epidermidis ATCC 12228 <2 <2 Staphylococcus aureus ATCC 25923 <2 <2 Staphylococcus aureus ATCC 43300 (MRSA) 256 32 Staphylococcus aureus PL 1 (inducible MRSA) <2 <2 Open in a separate window BIP minimum inhibitory concentration tests on bacterial strains.

Techniques: Concentration Assay